Although the applicability of small subunit ribosomal RNA (16S rRNA) sequences for
bacterial classification is now well accepted, the general use of these molecules has been …

A set of oligonucleotide primers capable of initiating enzymatic amplification (polymerase
chain reaction) on a phylogenetically and taxonomically wide range of bacteria is described …

THE early region of the small DNA tumour virus, simian virus 40 (SV40), is known to code
for at least two polypeptides, the t and T antigens (‘small t’ and ‘large T’). Both these …

Several physico-mechanical designs evolved in fish are currently inspiring robotic devices
for propulsion and maneuvering purposes in underwater vehicles. Considering the potential …

As a component of the response to acute stress, p53 has a well established role in protecting
against cancer development. However, it is now becoming clear that p53 can have a much …

Nucleic acid sequencing technology is bringing a much-needed phylogenetic perspective
into microbiology. There is no more fundamental and straightforн ward way to classify and …

Immunohistological staining of primary colorectal carcinomas with antibodies specific to p53
demonstrated gross overexpression of the protein in approximately 50% of the malignant …

Recombinant DNA methodology and rapid nucleotide sequence determinations have changed
the face of cell biology in the past few years. This technology offers powerful new tools to …

Currently, around 11 million people are living with a tumour that contains an inactivating
mutation of TP53 (the human gene that encodes p53) and another 11 million have tumours in …

The recently discovered p53-related genes, p73 and p63, express multiple splice variants
and N-terminally truncated forms initiated from an alternative promoter in intron 3. To date, no …